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Scholarly Articles

Use of dronabinol (delta-9-THC) in autism: A prospective single-case-study with an early infantile autistic child

(full–2010)

http://www.cannabis-med.org/data/pdf/en_2010_04_1.pdf

Can autism be triggered by acetaminophen activation of the endocannabinoid system?

(link to PDF–2010)

http://www.ncbi.nlm.nih.gov/pubmed/20628445

Variation in the human Cannabinoid Receptor (CNR1) gene modulates gaze duration for happy faces

(full–2011)

http://www.molecularautism.com/content/pdf/2040-2392-2-10.pdf

Consequences of cannabinoid and monoaminergic system disruption in a mouse model of autism spectrum disorders

(full–2011)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3137184/

Moderation of antipsychotic-induced weight gain by energy balance gene variants in the RUPP autism network risperidone studies

(full–2013)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3693401/

Autism-Associated Neuroligin-3 Mutations Commonly Disrupt Tonic Endocannabinoid Signaling

(full–2013)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3663050/

Evidence for a Common Endocannabinoid-Related Pathomechanism in Autism Spectrum Disorders

(link to full–2013)

http://www.sciencedirect.com/science/article/pii/S0896627313003619

Cannabinoid Receptor Type 2, but not Type 1, is Up-Regulated in Peripheral Blood Mononuclear Cells of Children Affected by Autistic Disorders

(abst–2013)

http://www.ncbi.nlm.nih.gov/pubmed/23585028

Alterations in the endocannabinoid system in the rat valproic acid model of autism

(abst–2013)

http://www.ncbi.nlm.nih.gov/pubmed/23643692

The in vitro GcMAF effects on endocannabinoid system transcriptionomics, receptor formation, and cell activity of autism-derived macrophages

(full–2014)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996516/

Defects in fatty acid amide hydrolase 2 in a male with neurologic and psychiatric symptoms

(full–2015)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423390/

Increased Cortical Inhibition in Autism-Linked Neuroligin-3R451C Mice Is Due in Part to Loss of Endocannabinoid Signaling

(full–2015)

http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0140638

Endocannabinoid signaling mediates oxytocin-driven social reward

(full–2015)

http://www.pnas.org/content/112/45/14084.full

Medical marijuana: review of the science and implications for developmental-behavioral pediatric practice

(abst–2015)

http://www.ncbi.nlm.nih.gov/pubmed/25650954

Endocannabinoid Signaling in Autism

(abst–2015)

http://www.ncbi.nlm.nih.gov/pubmed/26216231

Endocannabinoids and Mental Disorders

(abst–2015)

http://www.ncbi.nlm.nih.gov/pubmed/26408164

The basolateral amygdala γ-aminobutyric acidergic system in health and disease

(abst–2015)

http://www.ncbi.nlm.nih.gov/pubmed/26586374

β-Neurexins Control Neural Circuits by Regulating Synaptic Endocannabinoid Signaling

(abst–2015)

http://www.cell.com/cell/abstract/S0092-8674%2815%2900826-0?_returnURL=http%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0092867415008260%3Fshowall%3Dtrue

Oxytocin Enhances Pleasure of Social Interactions by Stimulating Production of “Bliss Molecule”

(news/abstract–2015)

http://neurosciencenews.com/oxytocin-anandamide-2926/

p21-activated kinase 1 restricts tonic endocannabinoid signaling in the hippocampus

(full–2016)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907698/

Endocannabinoid signaling in social functioning: an RDoC perspective

(full–2016)

http://www.nature.com/tp/journal/v6/n9/full/tp2016169a.html

Targeting anandamide metabolism rescues core and associated autistic-like symptoms in rats prenatally exposed to valproic acid

(full–2016)

http://www.nature.com/tp/journal/v6/n9/full/tp2016182a.html

Acetaminophen Use for Fever in Children Associated with Autism Spectrum Disorder

(full–2016)

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5044872

Involvement of TRPV1 in the Olfactory Bulb in Rimonabant-Induced Olfactory Discrimination Deficit.

(click “Full Text Links” for PDF–2016)

http://www.ncbi.nlm.nih.gov/pubmed/26875559

Deficient adolescent social behavior following early-life inflammation is ameliorated by augmentation of anandamide signaling

(abst–2016)

http://www.ncbi.nlm.nih.gov/pubmed/27453335

Pharmacological inhibition of fatty acid amide hydrolase attenuates social behavioural deficits in male rats prenatally exposed to valproic acid

(abst–2016)

http://www.sciencedirect.com/science/article/pii/S1043661816308660

Functions of synapse adhesion molecules neurexin/neurexins and neurodevelopmental disorders

(abst–2016)

http://www.sciencedirect.com/science/article/pii/S0168010216301419

Cannabinoids in Pediatrics

(full–2017)

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473390/

Endocannabinod Signal Dysregulation in Autism Spectrum Disorders: A Correlation Link between Inflammatory State and Neuro-Immune Alterations

(full–2017)

http://www.mdpi.com/1422-0067/18/7/1425/htm

Role of Endocannabinoids on Neuroinflammation in Autism Spectrum Disorder Prevention

(full–2017)

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5535348/

The Endocannabinoid System and Autism Spectrum Disorders: Insights from Animal Models

(full–2017)

http://www.mdpi.com/1422-0067/18/9/1916/htm

Rare genetic variants in the endocannabinoid system genes CNR1 and DAGLA are associated with neurological phenotypes in humans

(full–2017)

http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0187926

The Search for an Effective Therapy to Treat Fragile X Syndrome: Dream or Reality?

(full–2017)

https://www.frontiersin.org/articles/10.3389/fnsyn.2017.00015/full

Chronic Inflammatory Pain Impairs mGluR5-Mediated Depolarization-Induced Suppression of Excitation in the Anterior Cingulate Cortex

(abst–2017)

https://www.ncbi.nlm.nih.gov/pubmed/28520841

Synaptic functions of endocannabinoid signaling in health and disease

(abst–2017)

http://www.sciencedirect.com/science/article/pii/S0028390817302861

The Neurobiological Bases of Autism Spectrum Disorders The R451C-Neuroligin 3 mutation hampers the expression of long-term synaptic depression in the dorsal striatum

(abst–2017)

https://www.ncbi.nlm.nih.gov/pubmed/28921757

Plasma anandamide concentrations are lower in children with autism spectrum disorder

(full–2018)

https://molecularautism.biomedcentral.com/articles/10.1186/s13229-018-0203-y

An Inflammation-Centric View of Neurological Disease: Beyond the Neuron 

(full- 2018)

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871676/

Role of Striatal Direct Pathway 2-Arachidonoylglycerol Signaling in Sociability and Repetitive Behavior

(abst–2018) 

https://www.ncbi.nlm.nih.gov/pubmed/29458998

Palmitoylethanolamide as adjunctive therapy for autism: Efficacy and safety results from a randomized controlled trial

(abst–2018) 

https://www.ncbi.nlm.nih.gov/pubmed/29807317

Relationships between substance abuse/dependence and psychiatric disorders based on polygenic scores

(abst–2018) 

https://www.ncbi.nlm.nih.gov/pubmed/29974660

Sex specific autistic endophenotypes induced by prenatal exposure to valproic acid involve anandamide signaling

(abst–2018)

https://www.ncbi.nlm.nih.gov/pubmed/29968249

Cannabinoids: just like any other medication?

(abst–2018)

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(18)31611-8/fulltext

Oral cannabis extracts as a promising treatment for the core symptoms of autism spectrum disorder: Preliminary experience in Chilean patients

(full-2017)

https://www.jns-journal.com/article/S0022-510X(17)33120-9/fulltext

Brief Report: Cannabidiol-Rich Cannabis in Children with Autism Spectrum Disorder and Severe Behavioral Problems—A Retrospective Feasibility Study

(abstract-2018)

https://link.springer.com/article/10.1007/s10803-018-3808-2

Oral Cannabidiol Use in Children With Autism Spectrum Disorder to Treat Related Symptoms and Co-morbidities

(full-2018)

https://www.frontiersin.org/articles/10.3389/fphar.2018.01521/

 

United States Patent 6630507

Cannabinoids as antioxidants and neuroprotectants

http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=6630507.PN.&OS=PN/6630507&RS=PN/6630507